A common complaint in the musculoskeletal system is the anterior knee pain (AKP) or the so called patellofemoral pain syndrome (PFPS). The large number of contributing factors that lead to the symptoms make a proper diagnosis and targeted physiotherapeutic treatment management difficult. With regard to symptom-complex-oriented physiotherapeutic care, the question arises as to which therapy methods should be used for individuals with AKP. In order to be able to identify adequate physical therapy methods, an understanding of the clinical condition and the chosen treatment method is essential. This article aims to present a heuristic model of objectives and situational physiotherapeutic treatment methods.